Red desert
The Red Region is hell on earth. Not hell as in a devil ruling over the sins of the damned, but the Region is hot. It is a vast sprawling, red desert, so inhospitable that even the trees are trying to leave. Aside from the dangers of sandstorms, extreme heat and lack of water, the Red Region is home to the Red Plague, the most distructive disease in memory. Signs of the Red Plague are spots, swelling of the hands and throat, itches and, of course, painful death after three weeks. There is no known cure so it is quite good that the ancient wizards put down wards to stop the plague from escaping the Red Region.
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